A computational and physical perspective of molecules and the cell has changed the biochemical focus of biology. Mechanobiology studies the role of forces in the structure and function of molecules, cells, and tissues. This new view relies on structure, not only the traditional methods of x-ray crystallography and NMR spectroscopy but also structures from imaging by light and electron microscopy. The resulting mechanical and 3D models rely on powerful computational biology algorithms and approaches.
3D models rely on powerful computational biology algorithms and approaches.
New and powerful imaging methods are being developed and applied to capture dynamics – from molecules to tissues. Very stable AFM methods are able to measure small but significant forces in the folding and unfolding of proteins and DNA. The fluctuations in signal as a fluorescently marked protein or organelle passes through a beam of light can be transformed into an image of diffusion by Fluorescence Correlation Spectroscopy. The forces that drive the large-scale and coordinated migration of embryonic cells are being captured as strain maps of the developing zebrafish embryo through Hi-Lo DSLM.
to Centre for Bioimaging Sciences (CBIS) website
Make a difference by serving as a mentor to your juniors. This is a platform for our undergraduates to realize their potential through cultivation of professional as well as personal relationships with alumni mentors, who act as role models and provide guidance in terms of their personal and professional development. Through sharing of real-life insights and work experiences with your mentees, it equips and prepare them better as they venture into the workforce.This platform also provides opportunities to develop business contacts, access to industry information from experienced and successful alumni who have established themselves in their career.
Make a difference by serving as a mentor to your juniors. This is a platform for our undergraduates to realize their potential through cultivation of professional as well as personal relationships with alumni mentors, who act as role models and provide guidance in terms of their personal and professional development. Through sharing of real-life insights and work experiences with your mentees, it equips and prepare them better as they venture into the workforce.This platform also provides opportunities to develop business contacts, access to industry information from experienced and successful alumni who have established themselves in their career.
Make a difference by serving as a mentor to your juniors. This is a platform for our undergraduates to realize their potential through cultivation of professional as well as personal relationships with alumni mentors, who act as role models and provide guidance in terms of their personal and professional development. Through sharing of real-life insights and work experiences with your mentees, it equips and prepare them better as they venture into the workforce.This platform also provides opportunities to develop business contacts, access to industry information from experienced and successful alumni who have established themselves in their career.