CBIS Light Microscopy Core Archives - NUS Biological Sciences | NUS Biological Sciences

CBIS Light Microscopy Core

CBIS LM Core: InVi SPIM Lattice Pro

The InVi SPIM Lattice Pro provides a high level of flexibility for illuminating samples while maintaining ease of use and system stability. The beam shape can be tailored to suit your specific sample requirements – large field of view, high speed or optimal spatial resolution.
CBIS LM Core: Leica STELLARIS 8 FALCON (upright)

Leica STELLARIS 8 FALCON is a confocal point scanning system with FLIM, using a White Light Laser with pulse picker as excitation light source and a highly sensitive, prism-based spectral detection with adjustable bandwidth, to offer flexibility in both choosing excitation wavelength and defining emission range.
CBIS LM Core: Live-SR spinning disk confocal with TIRF

This system is capable of super-resolution live-cell imaging at high speed with minimal photodamage, or extremely thin optical sections using TIRF.
CBIS LM Core: Total Internal Reflection Fluorescence Microscope (TIRF) _1

TIRF_1 is optimized for long term live cell TIRF imaging, to study membrane dynamics at the cell basal membrane, of actin, cellular adhesion, cell movement, vesicle, protein tracking, etc.
CBIS LM Core: Leica Cryostat 1850

The Leica CM1850 cryostat design incorporates emphasis on power savings,increased efficiency and operator safety.
CBIS LM Core: UltraView Vox Spinning Disk

The PerkinElmer UltraView VoX is an optimum system for live cell imaging. It consists of Yokogawa® CSU-X1 spinning disk head, EM-CCD camera, ProSync control box, photoKinesis unit etc.
CBIS LM Core: 3I diSPIM

Live imaging directly involves inevitable tradeoffs of spatial resolution, temporal resolution and phototoxicity. This is especially true when interrogating imaging in three dimensions and/or three-dimensional samples over time (3D and/or 4D imaging) to obtain a complete picture of many dynamic subcellular processes.
CBIS LM Core: Zeiss LSM 900 with Dynamics Profiler

The LSM 900 offers super-resolution and improved SNR via the Airyscan detector, while the Dynamics Profiler makes it easy to measure the concentration and spatial diffusion patterns of fluorescent molecules.
CBIS LM Core: FLUOVIEW FV3000

The new Olympus FLUOVIEW FV3000 confocal has been setup in confocal core since March 2017. FV3000 is designed not only for high sensitivity and speed imaging for live cell on 2D-6D (x,y,λ,z,t,p), but also microplate imaging and complex screening.