CBIS Seminar: Force-dependent interaction between talin and full-length vinculin by Wang Yinan
Friday, 30 APR 2021 | Talin and vinculin are part of a multi-component system involved in mechanoenzyme in cell-matrix adhesions. Both exist in autho-inhibited forms, and activation of vinculin requires binding to mechanically activated talin, yet how forces affect talin’s interaction with vinculin has not been investigated.