TAN YONG ZI
Assistant Professor
NUS Presidential Young Professorship (PYP)
Department of Biological Sciences
National University of Singapore
16 Science Drive 4
Singapore 117558
Singapore
Joint appointment with Disease Intervention Technology Laboratory (DITL), A*STAR
Lab Website:
6516 7835
yztan@nus.edu.sg
Academic Qualifications
Post-doctoral Fellow, The Hospital for Sick Children (Canada), 2021
Ph.D., Columbia University (United State of America), 2019
B.Sc., Imperial College London (United Kingdom), 2013
Research Areas
Cryo-EM, Structural Biology, Membrane Proteins, Diabetes, Cancer, Methods Development, Biochemistry
Selected Publications (out of 21 publications)
-
Tan, Y.Z., Zhang, L., Rodrigues, J., Zheng, R.B., Giacometti, S.I., Rosário, A.L., Kloss, B., Dandey, V.P., Wei, H., Brunton, R., Raczkowski, A.M., Athayde, D., Catalão, M.J., Pimentel, M., Clarke, O.B., Lowary, T.L., Archer, M., Niederweis, M., Potter, C.S., Carragher, B. and Mancia, F., 2020. Cryo-EM Structures and Regulation of Arabinofuranosyltransferase AftD from Mycobacteria. Molecular Cell, 78(4), pp.683-699.
-
Kim, J.*, Tan, Y.Z.*, Wicht, K.J., Erramilli, S.K., Dhingra, S.K., Okombo, J., Vendome, J., Hagenah, L.M., Giacometti, S.I., Warren, A.L., Nosol, K., Roepe, P.D., Potter, C.S., Carragher, B., Kossiakoff, A.A., Quick, M., Fidock, D.A. and Mancia, F., 2019. Structure and drug resistance of the plasmodium falciparum transporter pfcrt. Nature, 576(7786), pp.315-320. *Equal contribution
-
Tan, Y.Z.*, Aiyer, S.*, Mietzsch, M.*, Hull, J.A., McKenna, R., Grieger, J., Samulski, R.J., Baker, T.S., Agbandje-McKenna, M. and Lyumkis, D., 2018. Sub-2 Å Ewald Curvature Corrected Structure of an AAV2 Capsid Variant. Nature communications, 9. *Equal contribution
-
Tan, Y.Z., Baldwin, P.R., Davis, J.H., Williamson, J.R., Potter, C.S., Carragher, B. and Lyumkis, D., 2017. Addressing preferred specimen orientation in single-particle cryo-EM through tilting. Nature methods, 14(8), p.793.
-
Davis, J.H.*, Tan, Y.Z.*, Carragher, B., Potter, C.S., Lyumkis, D. and Williamson, J.R., 2016. Modular assembly of the bacterial large ribosomal subunit. Cell, 167(6), pp.1610-1622. *Equal contribution