TAN YONG ZI

TAN YONG ZI

TAN YONG ZI

Assistant Professor

NUS Presidential Young Professorship (PYP)

Department of Biological Sciences
National University of Singapore
16 Science Drive 4
Singapore 117558
Singapore

Joint appointment with Disease Intervention Technology Laboratory (DITL), A*STAR

Lab Website:

www.tyzlab.com

6516 7835
yztan@nus.edu.sg


Academic Qualifications

Post-doctoral Fellow, The Hospital for Sick Children (Canada), 2021

Ph.D., Columbia University (United State of America), 2019

B.Sc., Imperial College London (United Kingdom), 2013

Research Areas

Cryo-EM, Structural Biology, Membrane Proteins, Diabetes, Cancer, Methods Development, Biochemistry

Selected Publications (out of 21 publications)

  1. Tan, Y.Z., Zhang, L., Rodrigues, J., Zheng, R.B., Giacometti, S.I., Rosário, A.L., Kloss, B., Dandey, V.P., Wei, H., Brunton, R., Raczkowski, A.M., Athayde, D., Catalão, M.J., Pimentel, M., Clarke, O.B., Lowary, T.L., Archer, M., Niederweis, M., Potter, C.S., Carragher, B. and Mancia, F., 2020. Cryo-EM Structures and Regulation of Arabinofuranosyltransferase AftD from Mycobacteria. Molecular Cell, 78(4), pp.683-699.

  2. Kim, J.*, Tan, Y.Z.*, Wicht, K.J., Erramilli, S.K., Dhingra, S.K., Okombo, J., Vendome, J., Hagenah, L.M., Giacometti, S.I., Warren, A.L., Nosol, K., Roepe, P.D., Potter, C.S., Carragher, B., Kossiakoff, A.A., Quick, M., Fidock, D.A. and Mancia, F., 2019. Structure and drug resistance of the plasmodium falciparum transporter pfcrt. Nature, 576(7786), pp.315-320. *Equal contribution

  3. Tan, Y.Z.*, Aiyer, S.*, Mietzsch, M.*, Hull, J.A., McKenna, R., Grieger, J., Samulski, R.J., Baker, T.S., Agbandje-McKenna, M. and Lyumkis, D., 2018. Sub-2 Å Ewald Curvature Corrected Structure of an AAV2 Capsid Variant. Nature communications, 9. *Equal contribution

  4. Tan, Y.Z., Baldwin, P.R., Davis, J.H., Williamson, J.R., Potter, C.S., Carragher, B. and Lyumkis, D., 2017. Addressing preferred specimen orientation in single-particle cryo-EM through tilting. Nature methods, 14(8), p.793.

  5. Davis, J.H.*, Tan, Y.Z.*, Carragher, B., Potter, C.S., Lyumkis, D. and Williamson, J.R., 2016. Modular assembly of the bacterial large ribosomal subunit. Cell, 167(6), pp.1610-1622. *Equal contribution

Full updated list on Google scholar