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Maitreyee
Sharma
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My research
work is focused on the purification and characterization of
a novel anticoagulant toxin from the venom of Indian Daboia
russelli. I am interested in understanding the mechanism
of action and the structure-function relationship of this toxin.
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Nityanand
Jha
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I am trying
to purify neprilysin, a protein from the venom of king cobra
(Ophiophagus hannah). To achieve this goal I am using
gel filtration and ion exchange chromatography. |
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Maansi
Malhotr
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The aim
of my project is to chemically synthesize a zinc-binding scaffold
from atrolysin C, a metalloproteinase from Crotalus atrox
(western diamondback rattle snake). |
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Lise
Lafolie
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I purified
the ryncolin protein from the venom of Cerberus ryncolin,
with the use of gel filtration and ion exchange chromatography.
The ryncolin protein is predicted to have an effect on blood
coagulation and platelet aggregation. |
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Shan
Arthi
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Janani
Raveendran
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Arun
Chandramohan
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Project: I worked on the purification and charecterization
of a weak toxin homolog from the venom of Ophiophagus
hannah.
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Gul
Gizem Korkut
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Project: During my studies in Prof. Kini's lab, my aim
was to understand the toxin profile of mallee black-backed
snake, Parasuta nigriceps, which was not studied
before. I constructed a partial cDNA library of the snake,
using its venom gland. The toxin genes found in the library
include serine protease inhibitors, three-finger toxins,
phospholipase A2, nerve growth factors, c-type lectin and
CRISPs.
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Sanchareeka
Dey
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Project: I worked with isolation
and purification of novel anticoagulants from the venom of
Naja nigricollis.
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Cassandra
M Modahl
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Project: During my semester abroad at NUS, I studied intraspecific
venom variation in Pakistan cobras (Naja naja)
from colonies kept at venom extraction facilities. The aim
of this study was to analyze factors such as age, gender,
size, locality, diet, and genetic relations responsible
for venom variation. The result of this study has practical
applications in future venom research and antiserum production
since venom for those purposes is collected from established
captive colonies.
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OmPraba
Gurusamy
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Project: We were interested
in analyzing the venom profile of colubridae snake-Cerberus
rynchops (dog-faced water snake) belonging to the family
homalopsidae. So far, venom compositions of snakes of homalopsidae
family are not known. Overall, our combined approach of transcriptomics
and proteomics revealed that C. rynchops venom was
among the least complex snake venom characterized to date
but contains new family of snake venom proteins.
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Edward
Goldring
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Project: I constructed a cDNA library
of the mangrove catsnake, Boiga dendrophila, and
sequenced ESTs.
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Prof.
Stephen Mackessy
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Project: I am Prof. Stephen
Mackessy from the University of Northern Colorado. I worked
with the construction of cDNA library from the venom gland
of Thelotornis.
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Lab Members
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