|
|
|
Veena S. Rao, PhD |
Current institute: Thrombosis Research Institute, India |
Jeremiah S. Joseph, PhD
|
Current institute: The SCRIPPS Reseach Institute, USA
|
Selvanayagam Nirthanan, PhD
|
Current institute: Griffith university, Australia
|
Rajamani Lakshminarayanan, PhD
|
Project: I studied the effect of proteins from egg shells on biomineralization.
Current Institute: Singapore Eye Research Institute, Singapore |
Huang Minzhou, PhD
|
Current institute: University of Pennsylvania, USA
|
Gong Jianping, PhD
|
|
Zhang Wen Sheng, PhD
|
|
Pung Yuh Fen, PhD
|
Project: I have isolated two novel proteins from king cobra venom and deciphered their physiological role and mechanism.
|
Pawlak Joanna, PhD
|
Project: My project focussed on the structural and functional characterization of novel toxins - potential novel research tools and therapeutic agents.
Current institute: The SCRIPPS Reseach Institute, USA
|
Syed Rehana, PhD
|
Project: My research involved the purification and characterization of a novel protein from the venom of snakes.
|
Dileep Gangadharan N R A, PhD
|
Project: I studied the structure and structure-function relationships of two proteins from a novel family of snake venom proteins called waprins
|
Md Abu Reza, PhD
|
Project: I determined the structural differences of venom proteins with their counterpart in the plasma at cDNA level; Characterized the respective genes; Identified and characterized the promoters of the genes to understand their regulation of expression.
Current institute: Rajshahi University, Bangladesh |
Kang Tse Siang, PhD
|
Project: α-conotoxins and χ /λ-conotoxins are short peptides with the same four conserved cysteines, but with distinct disulfide pairing (C1-3, C2-4 and C1-3, C2-4 respectively) resulting in globular and ribbon conformations. Through sequence alignment and subsequent studies using synthetic analogues, we have identified the importance of proline in the first intercysteine loop and C-terminal amide for the differential folding of these peptides. The folding propensities, as determined by coelution with regiospecifically synthesized conformers and NMR spectroscopy, indicate that these structural features act as conformations switches. Consequent conformation changes substantially impact the binding affinity of ImI conotoxin analogues to Aplysia Acetylcholine binding protein. The compact framework of these conotoxins present as attractive mini-protein scaffolds for presenting bioactive segments. As such, we have introduced RGD and KTS tripeptide sequences to design inhibitors of αIIbβ3 and α1β1 integrin receptors in this scaffold.
Current institute: The SCRIPPS Reseach Institute, USA
|
| Yajnavalka Banerjee, PhD
|
Project: I studied the interaction between two anticoagulant three finger toxins that form a complex, isolated from the venom of snake, and using it as a model to gain an insight into the intricacies of protein-protein interaction using biophysical techniques such as CD, ITC, GEMMA and X-ray crystallography.
|
Teo Chung Pin - Graduate student
|
Project: My work involved the identification of binding partner for ohanin in the central nervous system. |
| Nandha Kishore, PhD
|
Project: I have isolated and characterized novel proteins from the venom of Ophiophagus hannah (King cobra).
Current institute: University of Heidelberg
|
| Koh Cho Yeow, PhD
|
Project: My project involved the isolation and characterization of new anticoagulants from tick salivary gland extracts.
|
Lab Alumni
|
.gif){kind=spacer}
