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Key Publications For Snake Venom Prothrombin Activators

Reviews :

1. Kini, R.M., Morita, T. and Rosing, J.: Classification and nomenclature of prothrombin activators isolated from snake venoms.  Thrombos. Haemostas.85, 710-711, 2001. See also http://www.med.unc.edu/isth/snake.htm

2. Joseph, J. S., Rao, V. S. and Kini, R. M.: Snake venom prothrombin activators homologous to blood coagulation factor Xa. Haemostasis, 31, 234-240, 2002.

3. Joseph, J. S. and Kini, R. M.: Snake venom prothrombin activators similar to blood coagulation factor Xa. Curr. Drug Targets Cardiovasc. Haematol. Dis., 4, 397-416, 2004.

4. Kini, R. M.: The intriguing world of prothrombin activators from snake venoms. Toxicon, 45, 1133-1145, 2005.

5. Reza, M. A. and Kini, R. M.: Prothrombin activators from Australian snakes. Toxin Rev., 25, 257-290, 2006.

Book chapters :

1. Kini, R. M., Joseph, J. S. and Rao, V. S.: Prothrombin activators from snake venoms. In: Perspectives in Molecular Toxinology. Mènez, A. (Ed) John Wiley, Chichester, England, pp. 341-355, 2002.

Research papers :

1. Joseph, J. S., Chung, M. C. M., Jeyaseelan, K. and Kini, R. M.: Amino acid sequence of trocarin, a prothrombin activator from Tropidechis carinatus venom: Its structural similarity to coagulation factor Xa.  Blood, 94, 621-631, 1999.

2. Joseph, J. S., Chung, M. C. M., Mirtschin, P. J. and Kini, R. M.: Effect of snake venom procoagulants on snake plasma: implications for the coagulation cascade of snakes. Toxicon 40, 175-183, 2002.

3. Rao, V. S. and Kini, R. M.: Pseutarin C, a prothrombin activator from Pseudonaja textilis venom: Its structural and functional similarity to mammalian coagulation factor Xa-Va complex. Thrombos. Haemos.88, 611-619, 2002.

4. Gao, R., Kini, R. M. and Gopalakrishnakone, P.: A novel prothrombin activator from the venom of Micropechis ikaheka: isolation and characterization. Arch. Biochem. Biophys.408, 87-92, 2002.

5.  Rao, V. S., Joseph, J. S. and Kini, R. M.: Group D prothrombin activators from snake venom are structural homologues of mammalian blood coagulation factor Xa.  Biochem. J.369, 635-642, 2003.

6. Joseph, J. S., Valiyaveettil, M., Gowda, D. C. and Kini, R. M.: Occurrence of O-linked Xyl-GlcNAc and Xyl-Glc disaccharides in trocarin, a factor Xa homolog from snake venom. J. Thrombos. Haemos.1, 545-550, 2003.

7. Rao, V. S., Swarup, S. and Kini, R. M.: The nonenzymatic subunit of pseutarin C, a prothrombin activator from common brown snake (Pseudonaja textilis) venom, shows structural similarity to mammalian coagulation factor V. Blood, 102, 1347-1354, 2003.

8. Joseph, J. S., Thirumangalathu, S., Tsang, F., Wong, F. W. S. and Kini, R. M.: Trocarin, a blood coagulation factor Xa homologue from snake venom, causes inflammation and mitogenesis. Toxicon, 42, 769-776, 2003.

9. Rao, V. S., Swarup, S. and Kini, R. M.: The catalytic subunit of pseutarin C, a group C prothrombin activator from the venom of Pseudonaja textilis, is structurally similar to mammalian blood coagulation factor Xa. Thrombos. Haemostas., 92, 509-521, 2004.

10. Reza, M. A., Swarup, S. and Kini, R. M.: Two parallel prothrombin activator systems in Australian rough scaled snake (Tropidechis carinatus): structural comparison of venom prothrombin activator with blood coagulation factor X. Thrombos. Haemostas., 93, 40-47, 2005.

11. Le, T. N. M., Reza, M. A., Swarup, S. and Kini, R. M.: Gene duplication of coagulation factor V and origin of venom prothrombin activator in Pseudonaja textilis snake. Thrombos. Haemostas., 93, 420-429, 2005.

12. Reza, M. A., Le, T. N. M., Swarup, S. and Kini, R. M.: Molecular evolution caught in action: gene duplication and evolution of molecular isoforms of prothrombin activators in Pseudonaja textilis (brown snake). J. Thrombos. Haemostas., 4, 1346-1353, 2006.

13. Reza, M. A., Swarup, S. and Kini, R. M.: Gene structures of two functionally diverse prothrombin activators, Trocarin D and coagulation factor X in Tropidechis carinatus snake: gene duplication and recruitment of factor X gene to the venom gland. J. Thrombos. Haemostas., 5, 117-126, 2007.

 

 

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