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Key Publications For Neurotoxicity Of Candoxin

Review:

1.   Nirthanan, S., Gopalakrishnakone, P., Gwee, M. C. E., Khoo, H. E. and Kini, R. M.: Non-conventional toxins from elapid venomsToxicon, 41, 397-407, 2002.

Research papers:

1.   Nirthanan, S., Charpantier, E., Gopalakrishnakone, P., Gwee, M. C. E., Khoo, H. E., Cheah, L. S., Bertrand, D. and Kini, R. M.: Candoxin, a novel toxin from Bungarus candidus is a reversible antagonist of muscle (abgd) but a poorly reversible antagonist of neuronal a7 nicotinic acetylcholine receptors. J. Biol. Chem.  277, 17811-17820, 2002.

2.   Parvathy V. R., Chary, K. V. R., Kini, R. M. and Govil, G.: NMR studies of a neurotoxin (candoxin) from Bungarus candidus – Presence of predominantly b-sheet structure. Curr. Sci., 79, 219-222, 2000.

3.   Paaventhan, P., Joseph, J. S., Nirthanan, S., Rajaseger, G., Kini, R. M. and Kolatkar, P. R.: Crystallization and preliminary X-ray analysis of candoxin, a novel reversible neurotoxin from the Malayan krait Bungarus candidus. Acta Crystallogr. Section D, 59, 589-562, 2003.

4.   Parvathy V. R., Chary, K. V. R., Kini, R. M. and Govil, G.: Sequence specific 13C NMR assignments in a neurotoxin (candoxin) from Bungarus candidus. Magn. Reson. Chem. 39, 577-580, 2001.

5.   Nirthanan S., Charpantier, E., Gopalakrishnakone, P., Gwee, M. C. E., Khoo, H. E., Cheah, L. S., Bertrand, D. and Kini, R. M.: Neuromuscular effects of candoxin, a novel toxin from the venom of the Malayan krait (Bungarus candidus). Brit. J. Pharmacol. 139, 832-844, 2003.

6.   Parvathy V., R., Chary, K. V. R., Kini, R. M. and Govil, G.: Solution structure of candoxin, a novel three-finger toxin from the venom of Bungarus candidus. Arkivoc, 2006, 1-16, 2006.

 

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