Former Members

Postdoctoral Research Fellows

  • Nithin Pathoor (2022-2024): Explore super-resolution microcopy (DNA-PAINT, SRRF) for biological investigation and investigate their compatibility with FCS measurements.
  • Daniel AIK (2023-2024): Transmembrane bilayer coupling in live cell — an Alex-Imaging FCCS study
  • Zhong Jun (March 2023-September 2023): Cross scale biophysics and mechanobiology
  • Tang Wai Hoh (2022-2023): Deep learning reduces data requirements and allows real-time measurements in Imaging FCS
  • Harikrushnan Balasubramanian (2021-2022): Combinatorial DNA-PAINT for the Multiplexed Analysis of Cell Receptor Interactions
  • TAN Boon Wu, Aaron (2020-2022): Development of neuronal zebrafish primary cell culture and investigation of brain-cholesterol and sphingolipid bio-synthesis pathways
  • Sapthaswaran Veerapathiran (2019-2021): Wnt3 distribution in the zebrafish brain is determined by expression, diffusion and multiple molecular interactions.
  • Anjali GUPTA (2019-2020): To Hop or not to Hop: Exceptions in the FCS Diffusion Law.
  • Debjit ROY (2019): Investigation of the effects of ageing using Fluorescent Techniques.
  • Jagadish SANKARAN (2015-2019): Single microcolony diffusion analysis in Pseudomonas aeruginosa biofilms
  • NG Xue Wen (2017-2018): Quantitative three-dimensional (3D) mapping of biomolecular dynamics and organization in vitro and in vivo by SPIM-FCS
  • Nirmalya BAG (2014-2016): Imaging fluorescence correlation spectroscopy studies lipid membrane dynamics and organization: applications to the investigation of lipid bilayers, cell membranes and membrane active peptides
  • Radek MACHÁŇ (2012-2016): Combining Super-Resolution and FRAP with Imaging FCS, Dual-color ITIR-FCCS
  • FOO Yong Hwee (2010-2011): Quantitation of biological interactions in living cells using single wavelength fluorescence cross-correlation spectroscopy (SW-FCCS)
  • SHI Xianke (2008-2010): Applying fluorescence correlation spectroscopy in living zebrafish embryos
  • GUO Lin (2008-2009): Investigation of peptide-lipid interaction by fluorescence imaging and spectroscopy
  • Sebastian LEPTIHN (2007): Investigation of the Action Mechanism of Antimicrobial Peptides by Single Particle Tracking, Imaging, and Biochemical Methods
  • Lopamudra HOMCHAUDHURI (2006-2007): Lipid Membrane/Peptide Interactions
  • Balakrishnan KANNAN (2004-2007): EMCCD based FCS
  • Ph. D

  • Ashwin Venkata Subba Nelanuthala (2024): Investigating how morphogen gradients form in zebrafish embryos by the evaluation of Spatial Cross-Correlations on image stacks obtained using light sheet microscopy.
  • Daniel AIK (2024): Real-Time Measurements of Biological Membrane Dynamics by Imaging Fluorescence Correlation and Cross-Correlation Spectroscopy
  • Bitan Saha (2022): Investigating the morphogen dynamics and a novel role of BMP signalling during zebrafish development
  • Yong Xin Ee (2022): Molecular mechanism of dengue virus fusion and genome replication.
  • Harikrushnan Balasubramanian (2021): Investigation of Epidermal Growth Factor Receptor (EGFR) organization and dynamics on plasma membrane of live cells using fluorescence techniques.
  • Tang Wai Hoh (2020): Using deep learning for fluorescence spectroscopy analysis, time series analysis and generation of synthetic tabular data.
  • Sapthaswaran Veerapathiran (2019): Mapping the Expression Dynamics and Interactions of WNT3 in Live Zebrafish Embryos Using Fluorescence Techniques.
  • Sarala Neomi Tantirimudalige (2019): Investigation of Dengue Virus Dynamics and Cellular Attachment Using Fluorescence Cross-Correlation Spectroscopy and Single Particle Tracking.
  • Anjali GUPTA (2019): Role of membrane lipid composition in plasma membrane dynamics, organization and protein function
  • NG Xue Wen (2017): Quantitative three-dimensional (3D) mapping of biomolecular dynamics and organization in vitro and in vivo by SPIM-FCS
  • Andreas Karampatzakis (2017): Novel spectroscopic techniques for functional imaging of bacterial biofilms at microscopic level
  • Angela KOH (2017): Characterization of survival motor neuron dynamics by fluorescence correlation spectroscopy and neurexin2a function in a zebrafish model for spinal muscular atrophy
  • HUANG Shuangru (2016): Dynamics and organization of the epidermal growth factor receptor investigated by imaging fluorescence correlation spectroscopy
  • Sibel YAVAS (2016): Investigation of epidermal growth factor receptor in live cells by various fluorescence cross-correlation spectroscopy modalities
  • SUN Guangyu (2015): Application of bayesian model selection in fluorescence correlation spectroscopy (FCS) to Wnt3EGFP secretion and diffusion in zebrafish embryos
  • WANG Xi (2015): The study of nodal protein dynamics and interactions in living zebrafish embryos by fluorescence correlation and cross-correlation spectroscopy
  • Anand Pratap SINGH (2014): Light Sheet based fluorescence correlation and cross-correlation spectroscopy for quantitative measurements of bio-molecules in live cells
  • Nirmalya BAG (2014): Imaging fluorescence correlation spectroscopy studies lipid membrane dynamics and organization: applications to the investigation of lipid bilayers, cell membranes and membrane active peptides
  • MA Xiaoxiao (2014): Quantification of epidermal growth factor receptor dynamics and interactions in living cells by fluorescence correlation and cross-correlation spectroscopy
  • Rafi RASHID (2012):The biophysical properties of macromolecular crowders and their uptake, distribution and fate in cells
  • Tapan Kumar MISTRI (2012): Quantitative determination of the assembly of the Oct4-Sox2-DNA ternary complex and its relevance to pre-implantation development
  • Jagadish SANKARAN (2012): Imaging Fluorescence Correlation Spectroscopy: theory, simulations and applications to probe lipid-membrane dynamics
  • FOO Yong Hwee (2011): Quantitation of biological interactions in living cells using single wavelength fluorescence cross-correlation spectroscopy (SW-FCCS)
  • Manoj Kumar MANNA (2011): Identification of lipid nano-domains using FCS and ITIR-FCS on live cells
  • SHI Xianke (2010): Applying fluorescence correlation spectroscopy in living zebrafish embryos
  • GUO Lin (2010): Investigation of peptide-lipid interaction by fluorescence imaging and spectroscopy
  • PAN Xiaotao (2009): Investigation of microfluidics in channels and tissues by fluorescence correlation
  • LIU Ping (2008): The study of interactions of transmembrane receptors and intracellular signaling proteins in live cells by fluorescence correlation and cross-correlation spectroscopy
  • YU Lanlan (2007): Investigation of the interaction of antimicrobial peptides with lipids and lipid membranes
  • HWANG Ling Chin (2007): Single wavelength excitation fluorescence cross-correlation spectroscopy
  • M. Sc./Diploma

  • MENG Yumeng (2023): Measuring molecular dynamix in live zebrafish embryos using fluorescence correlation spectroscopy
  • Divya Dhasmana (2023): Understanding the protein dynamics of Frizzled and Wnt in embroyonic development
  • CHONG Hao Han (2023): Design of novel GTP sensor based on the ε-subunit from Bascillus species
  • ZHAO Wan Yu (2022): Towards the design of GTP metabolic sensor based on the ATP synthase epsilon chain ε-subunit from Bacillus species
  • ZHENG Junyi (2022): Single virus fluorescence fusion assay for the evaluation of antibody efficacy agiansta against infection
  • SIM Shao Ren (2022): Imaging FCS analysis using Convolutional Neural Networks
  • Kavitha RAJASEKHAR (2022): Investigation of dynamics of midkine and pleiotrophin during zebrafish development using FCS
  • Zhang Chi (2018): Study of the effects of anesthetics and fluidizers on lipid bilayers using imaging fluorescence correlation spectroscopy
  • LIM Shi Ying (2015): Investigation of cell membrane dynamics and organization by Imaging FCS
  • FAN Kaijie Herbert (2014): Measuring diffusion and quenching in microchannels
  • TEO Lin Shin (2012): Investigation of membrane properties in the central nervous system of Drosophila melanogaster studied by fluorescence correlation spectroscopy
  • TAY Wee Beng (2011): Production of laboratory video protocols for teaching purposes
  • Diane S. MORGAN1 (2006): Three dimensional flow profile measurements in microstructures using fluorescence correlation spectroscopy
  • LI Xinheng (2005): Synthesis and characterization of biofunctionalized gold nanoparticles
  • Anne THIEBAUD1 (2004): Dual-colour single molecule detection
  • NIU Lifang (2005): Strategies for detecting and studying biomolecules using surface plasmon fluorescence microscopy and spectroscopy
    1Exchange student from Swiss Federal Institute of Technology Lausanne (EPFL); co-supervision with Prof. Theo Lasser.
  • Research Assistants

  • Indira KARTIGAYEN (2018-2021): Enabling live imaging based developmental studies in zebrafish through transgenesis in terms of molecular based techniques
  • Catherine TEO Shi Hua (2013-2015): Study of cytoskeletal dynamics using multi-functional super-resolution imaging
  • Long Zhicheng (2009-10): Fluorescence Intensity Optimization by Pulsed Laser Excitation
  • LIU Jun (2005-2010): Study of lipid-peptide interaction using fluorescence spectroscopy
  • Har Jia Yi (2005-7): Host-pathogen interaction and tracking of bacterial invasion in tissues
  • B. Sc. (Hons.)

  • Muhammad Syakir Bin Mohamed Tajudin (2023): Wnt and Wntless interactions throgh Fluorescence (Cross) Correlation Spectroscopy
  • Nafeesah Binte Mohamed Ibrahim (2021): Oligomerization and Dynamics of Frizzled receptors investigated by fluorescence methods
  • Daniel AIK Ying Kia (2019): Application of Fluorescence Correlation Spectroscopy to understand the impact of additives on the micellar assembly of bar and liquid hand soaps
  • CHOW Su Tzen (2019): Cell Viability after Transfection Tested by Membrane Dynamics and Organization
  • GOH Jie Hui Corinna (2018): Epidermal Growth Factor Receptor Membrane Dynamics and Organization in Plasma Membranes Investigated by Fluorescence Spectroscopy
  • FAN Ricci (2018): Physico-chemical properties of emulsions studied by fluorescence spectroscopy
  • BUT Ka Pui (2018): Probing antibiotic diffusion in bacterial biofilms using a biofilm mimic
  • KOH Kai Jie (2017) : The investigation of peptide membrane interactions by imaging Fluorescence Correlation Spectroscopy
  • KWONG Mei Lin (2017) : Investigation of the action mechanism of the antimicrobial peptide, Aurein 1.2, by fluorescence spectroscopy
  • KOO Haoming (2017) : Experimental demonstration of a bio-laser
  • OWH Wei Le (2017): Anisotropy imaging to probe cell membrane dynamics and organisation
  • ONG Wei Yee (2016): Investigation of dengue proteins using fluorescence spectroscopy
  • LIU Yanting (2016): Determination of dimerization of Epidermal Growth Factor Receptor using genetic tags in live cells
  • TAN Jianwei Benedict (2015): Structural dynamic of dengue virus by single-molecule FRET
  • SIM Chun Siang (2015): Investigation of cell membrane organisational asymmetry by imaging fluorescence correlation spectroscopy
  • LAU Jing Yi Clara (2015): Investigation of lipid droplet fusion in live cells
  • Syed Hassan B SYED ZAINAL (2015): The measurement of molecular interactions using fluorescence cross-correlation spectroscopy
  • LIM Shi Ying (2014): Investigation of cell membrane structure and organization by fluorescence correlation spectroscopy
  • TOH Kah Huay Caroline (2013): Measuring reactions in microchannels
  • YAP Hui Xin Darilyn (2013):The measurements of lipid bilayer and cell membrane dynamic between 20-40oC by fluorescence spectroscopy
  • NG Xue Wen (2013): Dynamics and interactions of the transcription factors c-Fos and c-Jun in cell nuclei determined by fluorescence cross-correlation spectroscopy
  • FAN Kaijie Herbert (2012): Measuring diffusion and reactions in microchannels
  • Md Na'Im B SA'DOLLAH (2010): Single molecule fluorescence studies for the determination of protein dynamics on cell membranes
  • GOH Jun Lee (2010): Investigation of Cell Motility and Membrane Diffusion by Imaging Fluorescence Correlation Spectroscopy
  • NG Wei Ping (2010): Quantification of dimer formation between transcription factors on specific DNA elements
  • LOW Wei Wen (2010): Effect of Crowders on the Diffusion And Polymerisation of Actin.
  • ONG Li Bing (2008): Determination of the Action of Antimicrobial Peptides
  • SIOW Li Yan (2008): Rotational fluorescence correlation spectroscopy for the study of biomolecules
  • GOH Beng Hwa (2008): Measuring Reactions in Microchannels
  • SOH Xinyi (2008): Investigation of Cell Membrane Heterogeneity
  • ANG Kailian, Priscilla (2008 co-supervision): Assessing the Biocompatibility and Biosensing Property of Supported Lipid Bilayer on Diamond
  • LOW Qin Tian (2007): Measuring Reactions in Microchannels
  • CHOH Thian Fong, Carissa (2007): Cell membrane heterogeneity as seen by different molecules
  • YANG Shihong (, co-supervision): Quantifying microchannel cell transport with confocal fluorescence correlation spectroscopy
  • HONG Yi Mian (2006) : Molecular Diffusion Measurement In Lipid Bilayers Over Wide Concentration Ranges – A Comparative Study
  • LIM Wanrong (2006) : Determination Of Biomolecular Interactions By Fluorescence Cross-Correlation Spectroscopy
  • FOO Willy (2005) : Investigation Of Epidermal Growth Factor Receptors In Living Cells By Fluorescence Spectroscopy
  • AW Cai Li, Jade (2005): Characterization Of Graft-Polymerized Surfaces By Fluorescence Correlation Spectroscopy
  • FOK Han Yew, Marcus (2005): Rotational Fluorescence Correlation Spectroscopy For The Study Of Biomolecules
  • TAN Minyi,Shawn (2004): Determination Of The Aggregation Number Of Lipopolysaccharides By Fluorescence Correlation Spectroscopy
  • FOO Yong Hwee (2003): Interaction Of Antimicrobial Peptides With Lipid Membranes: A Model Membrane Study
  • Visitors

  • Alexandra Sofia Antunes de Sousa (UiT The Arctic University of Norway, Norway, June - July 2024, 2 months)
  • Junrui Cui (University of Toronto, Canada, May - July 2024, 3 months)
  • Ping QIN (Hong Kong Baptist University, Hong Kong, 2023 - 2024, 2 months)
  • Lisa POLZER (Freie Universität Berlin, Germany, 2023, 4 months)
  • LEE Donghwa (National University of Singapore, Singapore, 2023, 4 months of Undergraduate Research Opportunities Programme in Science)
  • Nandula Gopal Krishna (Science Research Program (highschool), Singapore, 2023, 2 months)
  • Lukas TAN Zheng Jie (Science Research Program (highschool), Singapore, 2023, 2 months)
  • Ian WANG (Science Research Program (highschool), Singapore, 2023, 2 months)
  • Varshini Anand (Smith college, Northampton, MA, United States, June - September 2022, 4 months)
  • WEI Minping (China, 2021 - 2022, 1 year)
  • Zahra (Nadia) SAADATMAND (La Trobe University, Australia, 2019 - 2022, 3 years)
  • Sarah Man Sze CHENG (The Hong Kong University of Science and Technology, Hong Kong, 2022, 2 months)
  • Diptatanu DAS (Indian Institute of Science Education and Research, Kolkata, 2021 - 2022, 5 months)
  • Akshat LOHIYA (Indian Institute of Technology, Delhi, 2021, 3 months)
  • Danqin LU (East China Normal University, China, 2019 - 2020, 1 year)
  • Yuting LI (University of Science and Technology of China, China, 2019, 2 months)
  • Ryosuke FUKUSHIMA (Hokkaido University, Japan, 2019, 2 months)
  • Dominic SCHATZ (Germany, 2 months)
  • Sonia MONTI (ZHdK Zürich, Switzerland, 2018, 6 months)
  • Sonja PAPAN (Marie-Curie-Gymnasium Dresden, Germany, 2018, 1 month)
  • Stefanie HACKL (Universitaet Wien, Austria, 2018 and 2016, 2 months each)
  • Madlen LUCKNER (Humboldt-Universität zu Berlin, Germany, 2018, 1 month)
  • Fariha RAHMAN (University of Toronto, 2017, 12 weeks)
  • Marie-Lena HARWARDT (Goethe-University Frankfurt, Germany, 2017, 15 weeks)
  • Ann-Christin ANDRES (Universitaet des Saarlandes, Germany, 2017, 2 months)
  • Andreas GRUETER (Universitaet des Saarlandes, Germany, 2016, 3 months)
  • Peter TÖRÖK (Imperial College, London, 2016, 3 weeks)
  • Amy WON (University of Toronto, 2016, 1 week)
  • Peter TÖRÖK (Imperial College, London, 2015, 2 weeks)
  • DONG Chaoqing (Shanghai Jiao Taong University, China, 2015, 1 week)
  • Abhay SHARMA (Indian Institute of Technology, Guwahati, India, 2015, 2 months)
  • Lavanya PAWAR (Indian Institute of Technology, Guwahati, India, 2015, 2 months)
  • Patrick KRAMER (University of Notre Dame, USA, 2013 - 2014, 10 months, funded by US Fulbright Scholarship)
  • Luc Veya (Swiss Federal Institute of Technology at Lausanne, EPFL, 2014, 3 weeks)
  • Tejaswi TAMMAREDDY (Andhra University, India, 2014, 8 weeks)
  • László VÍGH (Hungarian Academy of Sciences, 2013, 1 week)
  • Zsolt TÖRÖK (Hungarian Academy of Sciences, 2013, 1 week)
  • Imre GOMBOS (Hungarian Academy of Sciences, 2013, 1 week)
  • Agata PERNUS (University of Heidelberg and DKFZ, 2013, 2 weeks)
  • Antonija BURČUL (Zagreb University, Croatia, 2012, 4 months)
  • Bill Söderström ARNFLO (Stockholm University, Sweden, 2 weeks)
  • Aseem MISHRA (International Centre for Genetic Engineering and Biotechnology, India, 2012, 6 months, funded by Wellcome Trust-DBT India Alliance Early Career Fellowship)
  • Klaus YSERENTANT (University of Heidelberg, Germany, 2012, 4 months)
  • Adam OPALSKI (Warsaw University of Technology, Poland, 2012, 3 months)
  • Alok BHARTI (International School of Photonics, India, 2012, 3 months)
  • Alexandra PAUL (Universitaet des Saarlandes, Germany, 2011, 3 months)
  • K.V.S NARAIN (Indian Institute of Technology Roorkee, India, 2011, 8 weeks)
  • ZHANG Yiwen (Nanjing University, China, 2011, 10 weeks for final year project)
  • Jan KRIEGER (German Cancer Research Center, DKFZ, Germany, 2010, 2 weeks)
  • Thomas ELLINGHAUS (Universitaet Tübingen, Germany, 2009, 8 weeks)
  • Dagmar AUERBACH (Universitaet des Saarlandes, Germany, 2008/9, 3 months)
  • Shane Mason HODGE (University of Toronto, Canada, 2008, 5 weeks)
  • Marian ADAMSON (University of Michigan Ann Arbor, USA, 2007, 3 weeks)
  • Ming Yong (University of Michigan, Ann Arbor, USA, 2007, 3 weeks)
  • Corneliu BALAN (Polytehnica Bucharest, Romania, 2007, 2 weeks, funded by EERSS)
  • Mihaela GHEORGHIU (International Centre of Biodynamics, Bucharest, Romania, 2005, 1 month, funded by EERSS)
  • Eugen GHEORGHIU (International Centre of Biodynamics, Bucharest, Romania, 2005, 1 month, funded by EERSS)
  • Eugen GHEORGHIU (International Centre of Biodynamics, Bucharest, Romania, 2004, 2 weeks, funded by EERSS)
    • NUS
    • Biophysical Fluorescence Laboratory