Nithin Pathoor (2022-2024): Explore super-resolution microcopy (DNA-PAINT, SRRF) for biological investigation and investigate their compatibility with FCS measurements.
Daniel AIK (2023-2024): Transmembrane bilayer coupling in live cell — an Alex-Imaging FCCS study
Zhong Jun (March 2023-September 2023): Cross scale biophysics and mechanobiology
Tang Wai Hoh (2022-2023): Deep learning reduces data requirements and allows real-time measurements in Imaging FCS
Harikrushnan Balasubramanian (2021-2022): Combinatorial DNA-PAINT for the Multiplexed Analysis of Cell Receptor Interactions
TAN Boon Wu, Aaron (2020-2022): Development of neuronal zebrafish primary cell culture and investigation of brain-cholesterol and sphingolipid bio-synthesis pathways
Sapthaswaran Veerapathiran (2019-2021): Wnt3 distribution in the zebrafish brain is determined
by expression, diffusion and multiple molecular interactions.
Anjali GUPTA (2019-2020): To Hop or not to Hop: Exceptions in the FCS Diffusion Law.
Debjit ROY (2019): Investigation of the effects of ageing using Fluorescent Techniques.
Jagadish SANKARAN (2015-2019): Single microcolony diffusion analysis in Pseudomonas
aeruginosa biofilms
NG Xue Wen (2017-2018): Quantitative three-dimensional (3D) mapping of biomolecular dynamics and
organization in vitro and in vivo by SPIM-FCS
Nirmalya BAG (2014-2016): Imaging fluorescence correlation spectroscopy studies lipid membrane
dynamics and organization: applications to the investigation of lipid bilayers, cell membranes
and membrane active peptides
Radek MACHÁŇ (2012-2016): Combining Super-Resolution and FRAP with Imaging FCS, Dual-color
ITIR-FCCS
FOO Yong Hwee (2010-2011): Quantitation of biological interactions in living cells using single
wavelength fluorescence cross-correlation spectroscopy (SW-FCCS)
SHI Xianke (2008-2010): Applying fluorescence correlation spectroscopy in living zebrafish
embryos
GUO Lin (2008-2009): Investigation of peptide-lipid interaction by fluorescence imaging and
spectroscopy
Sebastian LEPTIHN (2007): Investigation of the Action Mechanism of Antimicrobial Peptides by
Single Particle Tracking, Imaging, and Biochemical Methods
Ashwin Venkata Subba Nelanuthala (2024): Investigating how morphogen gradients form in zebrafish embryos by the evaluation of Spatial Cross-Correlations on image stacks obtained using light sheet microscopy.
Daniel AIK (2024): Real-Time Measurements of Biological Membrane Dynamics by Imaging Fluorescence Correlation and Cross-Correlation Spectroscopy
Bitan Saha (2022): Investigating the morphogen dynamics and a novel role of BMP signalling during zebrafish development
Yong Xin Ee (2022): Molecular mechanism of dengue virus fusion and genome replication.
Harikrushnan Balasubramanian (2021): Investigation of Epidermal Growth Factor Receptor (EGFR) organization and dynamics on plasma membrane of live cells using fluorescence techniques.
Tang Wai Hoh (2020): Using deep learning for fluorescence spectroscopy analysis, time series analysis and generation of synthetic tabular data.
Sapthaswaran Veerapathiran (2019): Mapping the Expression Dynamics and Interactions of WNT3 in
Live Zebrafish Embryos Using Fluorescence Techniques.
Sarala Neomi Tantirimudalige (2019): Investigation of Dengue Virus Dynamics and Cellular
Attachment Using Fluorescence Cross-Correlation Spectroscopy and Single Particle Tracking.
Anjali GUPTA (2019): Role of membrane lipid composition in plasma membrane dynamics,
organization and protein function
NG Xue Wen (2017): Quantitative three-dimensional (3D) mapping of biomolecular dynamics and
organization in vitro and in vivo by SPIM-FCS
Andreas Karampatzakis (2017): Novel spectroscopic techniques for functional imaging of bacterial
biofilms at microscopic level
Angela KOH (2017): Characterization of survival motor neuron dynamics by fluorescence
correlation spectroscopy and neurexin2a function in a zebrafish model for spinal muscular
atrophy
HUANG Shuangru (2016): Dynamics and organization of the epidermal growth factor receptor
investigated by imaging fluorescence correlation spectroscopy
Sibel YAVAS (2016): Investigation of epidermal growth factor receptor in live cells by various
fluorescence cross-correlation spectroscopy modalities
SUN Guangyu (2015): Application of bayesian model selection in fluorescence correlation
spectroscopy (FCS) to Wnt3EGFP secretion and diffusion in zebrafish embryos
WANG Xi (2015): The study of nodal protein dynamics and interactions in living zebrafish
embryos by fluorescence correlation and cross-correlation spectroscopy
Anand Pratap SINGH (2014): Light Sheet based fluorescence correlation and cross-correlation
spectroscopy for quantitative measurements of bio-molecules in live cells
Nirmalya BAG (2014): Imaging fluorescence correlation spectroscopy studies lipid membrane
dynamics and organization: applications to the investigation of lipid bilayers, cell membranes
and membrane active peptides
MA Xiaoxiao (2014): Quantification of epidermal growth factor receptor dynamics and interactions
in living cells by fluorescence correlation and cross-correlation spectroscopy
Rafi RASHID (2012):The biophysical properties of macromolecular crowders and their uptake,
distribution and fate in cells
Tapan Kumar MISTRI (2012): Quantitative determination of the assembly of the Oct4-Sox2-DNA
ternary complex and its relevance to
pre-implantation development
Jagadish SANKARAN (2012): Imaging Fluorescence Correlation Spectroscopy: theory, simulations and
applications to probe lipid-membrane dynamics
FOO Yong Hwee (2011): Quantitation of biological interactions in living cells using single
wavelength fluorescence cross-correlation spectroscopy (SW-FCCS)
Manoj Kumar MANNA (2011): Identification of lipid nano-domains using FCS and ITIR-FCS on live
cells
SHI Xianke (2010): Applying fluorescence correlation spectroscopy in living zebrafish embryos
GUO Lin (2010): Investigation of peptide-lipid interaction by fluorescence imaging and
spectroscopy
PAN Xiaotao (2009): Investigation of microfluidics in channels and tissues by fluorescence
correlation
LIU Ping (2008): The study of interactions of transmembrane receptors and intracellular
signaling proteins in live cells by fluorescence correlation and cross-correlation spectroscopy
YU Lanlan (2007): Investigation of the interaction of antimicrobial peptides with lipids and
lipid membranes
HWANG Ling Chin (2007): Single wavelength excitation fluorescence cross-correlation spectroscopy
M. Sc./Diploma
MENG Yumeng (2023): Measuring molecular dynamix in live zebrafish embryos using fluorescence correlation spectroscopy
Divya Dhasmana (2023): Understanding the protein dynamics of Frizzled and Wnt in embroyonic development
CHONG Hao Han (2023): Design of novel GTP sensor based on the ε-subunit from Bascillus species
ZHAO Wan Yu (2022): Towards the design of GTP metabolic sensor based on the ATP synthase epsilon chain ε-subunit from Bacillus species
ZHENG Junyi (2022): Single virus fluorescence fusion assay for the evaluation of antibody efficacy agiansta against infection
Kavitha RAJASEKHAR (2022): Investigation of dynamics of midkine and pleiotrophin during zebrafish development using FCS
Zhang Chi (2018): Study of the effects of anesthetics and fluidizers on lipid bilayers using imaging fluorescence correlation spectroscopy
LIM Shi Ying (2015): Investigation of cell membrane dynamics and organization by Imaging FCS
FAN Kaijie Herbert (2014): Measuring diffusion and quenching in microchannels
TEO Lin Shin (2012): Investigation of membrane properties in the central nervous system of
Drosophila melanogaster studied by fluorescence correlation spectroscopy
TAY Wee Beng (2011): Production of laboratory video protocols for teaching purposes
Diane S. MORGAN1 (2006): Three dimensional flow profile measurements in
microstructures using fluorescence correlation spectroscopy
LI Xinheng (2005): Synthesis and characterization of biofunctionalized gold nanoparticles
Anne THIEBAUD1 (2004): Dual-colour single molecule detection
NIU Lifang (2005): Strategies for detecting and studying biomolecules using surface plasmon
fluorescence microscopy and spectroscopy
1Exchange student from Swiss Federal Institute of Technology Lausanne (EPFL);
co-supervision with Prof. Theo Lasser.
Research Assistants
Indira KARTIGAYEN (2018-2021): Enabling live imaging based developmental studies in zebrafish through transgenesis in terms of molecular based techniques
Catherine TEO Shi Hua (2013-2015): Study of cytoskeletal dynamics using multi-functional
super-resolution imaging
Long Zhicheng (2009-10): Fluorescence Intensity Optimization by Pulsed Laser Excitation
LIU Jun (2005-2010): Study of lipid-peptide interaction using fluorescence spectroscopy
Har Jia Yi (2005-7): Host-pathogen interaction and tracking of bacterial invasion in tissues
B. Sc. (Hons.)
Muhammad Syakir Bin Mohamed Tajudin (2023): Wnt and Wntless interactions throgh Fluorescence (Cross) Correlation Spectroscopy
Nafeesah Binte Mohamed Ibrahim (2021): Oligomerization and Dynamics of Frizzled receptors investigated by fluorescence methods
Daniel AIK Ying Kia (2019): Application of Fluorescence Correlation Spectroscopy to understand
the impact of additives on the micellar assembly of bar and liquid hand soaps
CHOW Su Tzen (2019): Cell Viability after Transfection Tested by Membrane Dynamics and
Organization
GOH Jie Hui Corinna (2018): Epidermal Growth Factor Receptor Membrane Dynamics and Organization
in Plasma Membranes Investigated by Fluorescence Spectroscopy
FAN Ricci (2018): Physico-chemical properties of emulsions studied by fluorescence spectroscopy
BUT Ka Pui (2018): Probing antibiotic diffusion in bacterial biofilms using a biofilm mimic
KOH Kai Jie (2017) : The investigation of peptide membrane interactions by imaging Fluorescence
Correlation Spectroscopy
KWONG Mei Lin (2017) : Investigation of the action mechanism of the antimicrobial peptide,
Aurein 1.2, by fluorescence spectroscopy
KOO Haoming (2017) : Experimental demonstration of a bio-laser
OWH Wei Le (2017): Anisotropy imaging to probe cell membrane dynamics and organisation
ONG Wei Yee (2016): Investigation of dengue proteins using fluorescence spectroscopy
LIU Yanting (2016): Determination of dimerization of Epidermal Growth Factor Receptor using
genetic tags in live cells
TAN Jianwei Benedict (2015): Structural dynamic of dengue virus by single-molecule FRET
SIM Chun Siang (2015): Investigation of cell membrane organisational asymmetry by imaging
fluorescence correlation spectroscopy
LAU Jing Yi Clara (2015): Investigation of lipid droplet fusion in live cells
Syed Hassan B SYED ZAINAL (2015): The measurement of molecular interactions using fluorescence
cross-correlation spectroscopy
LIM Shi Ying (2014): Investigation of cell membrane structure and organization by fluorescence
correlation spectroscopy
TOH Kah Huay Caroline (2013): Measuring reactions in microchannels
YAP Hui Xin Darilyn (2013):The measurements of lipid bilayer and cell membrane dynamic between
20-40oC by fluorescence spectroscopy
NG Xue Wen (2013): Dynamics and interactions of the transcription factors c-Fos and c-Jun in
cell nuclei determined by fluorescence cross-correlation spectroscopy
FAN Kaijie Herbert (2012): Measuring diffusion and reactions in microchannels
Md Na'Im B SA'DOLLAH (2010): Single molecule fluorescence studies for the determination of
protein dynamics on cell membranes
GOH Jun Lee (2010): Investigation of Cell Motility and Membrane Diffusion by Imaging
Fluorescence Correlation Spectroscopy
NG Wei Ping (2010): Quantification of dimer formation between transcription factors on specific
DNA elements
LOW Wei Wen (2010): Effect of Crowders on the Diffusion And Polymerisation of Actin.
ONG Li Bing (2008): Determination of the Action of Antimicrobial Peptides
SIOW Li Yan (2008): Rotational fluorescence correlation spectroscopy for the study of
biomolecules
GOH Beng Hwa (2008): Measuring Reactions in Microchannels
SOH Xinyi (2008): Investigation of Cell Membrane Heterogeneity
ANG Kailian, Priscilla (2008 co-supervision): Assessing the Biocompatibility and Biosensing
Property of Supported Lipid Bilayer on Diamond
LOW Qin Tian (2007): Measuring Reactions in Microchannels
CHOH Thian Fong, Carissa (2007): Cell membrane heterogeneity as seen by different molecules
YANG Shihong (, co-supervision): Quantifying microchannel cell transport with confocal
fluorescence correlation spectroscopy
HONG Yi Mian (2006) : Molecular Diffusion Measurement In Lipid Bilayers Over Wide Concentration
Ranges – A Comparative Study
LIM Wanrong (2006) : Determination Of Biomolecular Interactions By Fluorescence
Cross-Correlation Spectroscopy
FOO Willy (2005) : Investigation Of Epidermal Growth Factor Receptors In Living Cells By
Fluorescence Spectroscopy
AW Cai Li, Jade (2005): Characterization Of Graft-Polymerized Surfaces By Fluorescence
Correlation Spectroscopy
FOK Han Yew, Marcus (2005): Rotational Fluorescence Correlation Spectroscopy For The Study Of
Biomolecules
TAN Minyi,Shawn (2004): Determination Of The Aggregation Number Of Lipopolysaccharides By
Fluorescence Correlation Spectroscopy
FOO Yong Hwee (2003): Interaction Of Antimicrobial Peptides With Lipid Membranes: A Model
Membrane Study
Visitors
Alexandra Sofia Antunes de Sousa (UiT The Arctic University of Norway, Norway, June - July 2024, 2 months)
Junrui Cui (University of Toronto, Canada, May - July 2024, 3 months)
Ping QIN (Hong Kong Baptist University, Hong Kong, 2023 - 2024, 2 months)
Lisa POLZER (Freie Universität Berlin, Germany, 2023, 4 months)
LEE Donghwa (National University of Singapore, Singapore, 2023, 4 months of Undergraduate Research Opportunities Programme in Science)
Nandula Gopal Krishna (Science Research Program (highschool), Singapore, 2023, 2 months)
Lukas TAN Zheng Jie (Science Research Program (highschool), Singapore, 2023, 2 months)
Ian WANG (Science Research Program (highschool), Singapore, 2023, 2 months)
Varshini Anand (Smith college, Northampton, MA, United States, June - September 2022, 4 months)
Bill Söderström ARNFLO (Stockholm University, Sweden, 2 weeks)
Aseem MISHRA (International Centre for Genetic Engineering and Biotechnology, India, 2012, 6
months, funded by Wellcome Trust-DBT India Alliance Early Career Fellowship)
Klaus YSERENTANT (University of Heidelberg, Germany, 2012, 4 months)
Adam OPALSKI (Warsaw University of Technology, Poland, 2012, 3 months)
Alok BHARTI (International School of Photonics, India, 2012, 3 months)
Alexandra PAUL (Universitaet des Saarlandes, Germany, 2011, 3 months)
K.V.S NARAIN (Indian Institute of Technology Roorkee, India, 2011, 8 weeks)
ZHANG Yiwen (Nanjing University, China, 2011, 10 weeks for final year project)
Jan KRIEGER (German Cancer Research Center, DKFZ, Germany, 2010, 2 weeks)
Thomas ELLINGHAUS (Universitaet Tübingen, Germany, 2009, 8 weeks)
Dagmar AUERBACH (Universitaet des Saarlandes, Germany, 2008/9, 3 months)
Shane Mason HODGE (University of Toronto, Canada, 2008, 5 weeks)
Marian ADAMSON (University of Michigan Ann Arbor, USA, 2007, 3 weeks)
Ming Yong (University of Michigan, Ann Arbor, USA, 2007, 3 weeks)